Research
The Effects of Sika Deer Antler Peptides on 3T3-L1 Preadipocytes and C57BL/6 Mice via Activating AMPK Signaling and Gut Microbiota - Molecules, 2025
... Background: To explore the anti-obesity effects and mechanisms of sika deer velvet antler peptides (sVAP) on 3T3-L1 preadipocytes and in high-fat diet (HFD)-induced obese mice... This study identifies four novel oligopeptides in sVAP-3K as key components for anti-obesity effects, offering new evidence for developing natural weight-loss drugs from sika deer velvet...
Anti-fatigue effect of an enzymatically derived deer velvet extract through muscle damage recovery and improvement of antioxidant levels - 2024, ScienceDirect.com
... Deer velvet (DV) ...notably exhibits anti-fatigue properties; however, its specific mode of action is yet to be fully elucidated. ... These findings suggest the potential of YC-1101 as a nutraceutical adjunct in ameliorating fatigue, concurrently facilitating muscle damage recovery, and exerting antioxidant effects via the nuclear factor E2-related factor 2-Kelch-like ECH-associated protein-1 pathway...
Repair of Mechanical Cartilage Damage Using Exosomes Derived from Deer Antler Stem Cells n- Frontiers in Bioscience …, 2024
... Hydrogels loaded with exosomes (Exos) derived from antler stem cells (ASC-Exos) ... significantly promoted the repair of cartilage tissue damage. The level of cartilage repair in the experimental group (ASC-Exos) was higher than that in the positive control (human adipose-derived stem cells, hADSC-Exos) and negative control (dulbecco’s modified eagle medium) groups ....
Sika Deer Velvet Antler Peptide Exerts Neuroprotective Effect in a Parkinson's Disease Model via Regulating Oxidative Damage and Gut Microbiota - Pharmaceuticals, 2024
... this research was aimed at evaluating the neuroprotective effects of Sika Deer velvet antler peptide (VAP) ... , the administration of the VAP effectively reduced the dopaminergic neuron damage and reversed the neurobehavioral deficits. They also diminished microglia activation and apoptosis, all without any noticeable adverse effects. Additionally, the VAP was observed to beneficially alter the gut microbiota ...
Fermented antler extract attenuates muscle atrophy by regulating the PI3K/Akt pathway and inflammatory response in immobilization-treated C57BL/6J mice 2024 Food Science and Biotechnology
... Oral administration of FAE [fermented antler extract] increased grip strength, exercise performance, muscle mass, and volume in mice...
Protective Effect of Deer Heart Peptide on Cardiac Injury in Mice. 2024 - International Journal of Inflamation
... Significant improvement in myocardial disorders by deer heart peptide could be observed from heart tissue sections. The present study emphasizes the anti-inflammatory and antioxidant activity of deer heart peptide, an enzymatic digest of deer heart ...
Dietary supplementation of SAT and SANT, New Zealand deer velvet supplements, halts systemic LPS-induced neuroinflammation and sickness behaviour in mice - Journal of Functional Foods, 2024
... The two New Zealand velvet supplements, SAT and SANT reduced neuroinflammation and sickness behaviour through different mechanism...
Woman's 'Highly Unusual' Pneumonia Caused by Parasite-Tainted Deer Meat May 3, 2024 Florida, Yahoo
... detailed this week in the New England Journal of Medicine ... the 32-year-old Florida resident visited an emergency room ... the woman had recently prepared a deer carcass collected from her boyfriend’s hunting trip in Alabama. The woman cooked, served, and ate the venison ... tests came back positive for T. gondii ... her blood was chock full of the parasite ...
Conditioned Media from Deer Antler Stem Cells Effectively Alleviate Type 1 Diabetes Mellitus Possibly via Inhibiting the NF-κB Signaling Pathway - Frontiers in Bioscience Landmark, 2024
... Deer antler stem cells (AnSCs), a novel type of adult stem cells, significantly reduced liver injury, which was speculated to be achieved through the paracrine pathway...
Deer antler extract-nanoparticles exhibit co-nanozyme activity and targeting of prostate cancer cells - Journal of Functional Foods, 2024
... Deer antler water extract decreases prostate cancer cells viability. Especially with combined inhibitor of MET kinase...
Novel approach for hair growth stimulation by deer antler velvet extract-loaded nano-chitosomes and micro-spicule formulation - Journal of Drug Deliver Science and Technology, 2023
... Bioactive extracts from deer antler velvet (DAV) have the potential to stimulate hair growth ... Applying DAV extract-loaded CTS-MS gel to scalp skins for 14 and 28 days significantly improved hair growth and melanin content without skin irritation...
Deer antlers: the fastest growing tissue with least cancer occurrence - Cell Death & Differentiation, 2023
... The antler growth center is located in its tip ... antler extracts and RM cells/exosomes have been tried on different cancer models either in vitro or in vivo, and all achieved positive results. These positive experimental results together with the anecdotal folklore that regular consumption of velvet antler is living with cancer-free would encourage us to test antlers in clinic settings...
White-Tailed Deer Serum Kills the Lyme Disease Spirochete, Borrelia burgdorferi 2023 Vector-Borne and Zoonotic Diseases
... White-tailed deer (WTD) are considered to be noncompetent reservoirs for B. burgdorferi... we demonstrated that WTD serum effectively kills B. burgdorferi. The borreliacidal activity of WTD serum likely contributes to the inability of WTD to efficiently harbor and transmit B. burgdorferi...
Drinking deer milk could have health benefits, scientists suggest March 6, 2023 New Zealand, Stuff.co.nz
... Although none of the women gained weight they all gained muscle mass after drinking deer milk, without additional exercise, she said. “As we age, we lose muscle mass much more easily than we gain it, and we do need more proteins,” Von Hurst said...
Enzyme-derived deer velvet extract activate the immune response in cyclophosphamide-induced immunosuppressive mice, Food Science and Biotechnology, 2023
... Deer velvet (DV) is an oriental traditional medicine used to treat various diseases. The present study examined the effect of flavourzyme-derived DV extract (YC-1101) on macrophages and an immunosuppressed mouse model ... these results suggest that YC-1101 is an efficient natural ingredient that has an immune-enhancing effect, and it might be a potential functional food for improving immunity...
Elevated lead exposure in Australian hunting dogs during a deer hunting season - Environmental Pollution, 2023
... Blood was collected from 27 dogs ... The finding that BLLs (blood lead levels) more than doubled during the hunting season indicates that lead exposure is a risk in this context...
Pitt study recommends lead-content advisories on venison donated to food banks November 26, 2022 Pennsylvania, Pittsburgh Post-Gazette
... A University of Pittsburgh report on lead fragmentation in hunted deer, published in September in the American Journal of Public Health, was billed as the first study specifically focused on the presence of lead particles in venison donated by hunters to organizations that provide food to low income families... There is no safe level of lead in the human body...
Transcriptional sequencing analysis reveals the potential use of deer antler for “tonifying the kidney and strengthening bone” - Journal of Orthopaedic Surgery and Research, 2022
... Rats were treated with deer antler extract (DAE) prepared in advance ... The results demonstrate that DAE could jointly heighten renal function by maintaining renal homeostasis, combating renal fibrosis, and reducing renal inflammation by regulating ion transport. Furthermore, DAE can strengthen the bone system by stimulating osteoblast differentiation and regulating bone regeneration ...
Clinical Effectiveness of Ikgibohyeol-tang(Yìqìbǔxuè-tāng) and Deer Antler on Fatigue Symptoms and HRV Results in Outpatients at Korean Medical Hospital: A Retrospective Chart Review Study September 8, 2022, Journal of Korean Medicine
... After taking Ikgibohyeol-tang granules and Deer antler granules, the degree of discomfort with fatigue and accompanying symptoms decreased significantly compared to before taking them. After treatment, Autonomic nervous system activity, Stress resistance, Heart Stability increased, and Stress index, Degree of fatigue decreased significantly...